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\u8425\u6536\u89c4\u6a21\u5927\u5e45\u63d0\u5347\uff0c\u540c\u65f6\u7531\u4e8e\u591a\u6d41\u7a0b CDMO \u4e1a\u52a1\u5728\u53d1\u5c55\u9636\u6bb5\u5206\u644a \u8f83\u591a\u7684\u7814\u53d1\u6d4b\u8bd5\u76f8\u5173\u6210\u672c\u548c\u56fa\u5b9a\u8d44\u4ea7\u6298\u65e7\uff0cCDMO \u6bdb\u5229\u7387\u5728\u5f53\u5e74\u6709\u8f83\u660e\u663e\u7684\u4e0b\u6ed1\u3002\u516c\u53f8\u5728 2021 \u5e74 CDMO \u4ea7\u80fd\u9010\u6b65\u91ca\u653e\uff0c\u4f7f\u6bdb\u5229\u7387\u56de\u5347\u81f3\u4e0e 2019 \u5e74\u6301\u5e73\uff0c\u957f\u671f\u770b\u516c\u53f8\u53ef\u5728\u5feb\u901f\u63d0\u5347\u5927\u578b CDMO \u9879 \u76ee\u627f\u63a5\u80fd\u529b\u7684\u540c\u65f6\u4fdd\u6301\u76c8\u5229\u80fd\u529b\u7a33\u5b9a\u3002<\/p>\n<p id=\"156H45LP\">\u4ece 2019 \u81f3 2021 \u5e74\uff0c\u516c\u53f8\u7814\u53d1\u8d39\u7528\u7387\u6301\u7eed\u663e\u8457\u964d\u4f4e\uff0c\u7814\u53d1\u6548\u7387\u968f\u6280\u672f\u5e73\u53f0\u7684\u7a33\u5b9a\u5feb\u901f\u63d0\u5347\uff0c \u800c\u5176\u4ed6\u8d39\u7528\u6bd4\u7387\u53ca\u9500\u552e\u6210\u672c\u7387\u53d8\u52a8\u5e45\u5ea6\u6709\u9650\uff0c\u8425\u4e1a\u603b\u6210\u672c\u5360\u8425\u4e1a\u6536\u5165\u7684\u6bd4\u4f8b\u5728 2019\/2020\/2021 \u5e74 \u5206\u522b\u4e3a 122%\/96%\/74%\uff0c\u76c8\u5229\u80fd\u529b\u5feb\u901f\u5f3a\u5316\u3002<\/p>\n<p id=\"156H45LQ\">\u4e24\u5927\u4e1a\u52a1\u5ba2\u6237\u6570\u91cf\u53ca\u4e3b\u8981\u5ba2\u6237\u8d21\u732e\u6536\u5165\u540c\u6b65\u589e\u52a0\u3002\u5728 2019\/2020\/2021 \u5e74\uff0c\u516c\u53f8\u57f9\u517b\u57fa\u5ba2\u6237\u6570 \u91cf\u4e3a 222\/361\/518 \u5bb6\uff0cCDMO \u5ba2\u6237\u6570\u91cf\u4e3a 30\/33\/47 \u5bb6\uff0c\u4e24\u5927\u4e1a\u52a1\u5ba2\u6237\u6570\u7a33\u6b65\u63d0\u5347\u3002\u57f9\u517b\u57fa\u524d\u5341\u5927\u5ba2 \u6237\u7684\u6536\u5165\u91d1\u989d\u4e3a 1591\/3133\/6958 \u4e07\u5143\uff0c\u5448\u9010\u5e74\u500d\u589e\u8d8b\u52bf\uff0c\u4e3b\u8981\u53d7\u76ca\u4e8e\u90e8\u5206\u5ba2\u6237\u7684\u57f9\u517b\u57fa\u7528\u91cf\u968f\u7814 \u53d1\u9636\u6bb5\u7684\u63a8\u8fdb\u800c\u589e\u52a0\uff0c\u800c\u76ee\u524d\u5927\u90e8\u5206\u4f7f\u7528\u516c\u53f8\u57f9\u517b\u57fa\u7684\u65b0\u836f\u5904\u4e8e\u65e9\u671f\u7814\u53d1\u9636\u6bb5\uff0c\u636e\u6b64\u9884\u8ba1\u77ed\u671f\u5185 \u5c06\u6709\u5927\u91cf\u5ba2\u6237\u5bf9\u516c\u53f8\u7684\u6536\u5165\u8d21\u732e\u660e\u663e\u63d0\u5347\u3002CDMO \u4e3b\u8981\u5ba2\u6237\uff08\u6536\u5165\u89c4\u6a21\u5927\u4e8e 500 \u4e07\uff09\u7684\u6536\u5165\u91d1\u989d\u4e3a 2067\/5173\/6071 \u4e07\u5143\uff0c\u4ea6\u5b9e\u73b0\u4e86\u5feb\u901f\u589e\u957f\uff0c\u4e3b\u8981\u53d7\u76ca\u4e8e\u516c\u53f8\u627f\u63a5\u5927\u578b CDMO \u9879\u76ee\u7684\u80fd\u529b\u589e\u5f3a\uff0c\u5728 2020 \u5e74\u5927\u578b CDMO \u9879\u76ee\u8d21\u732e\u7684\u6536\u5165\u91d1\u989d\u660e\u663e\u589e\u52a0\u3002<\/p>\n<p class=\"f_center\"><img decoding=\"async\" src=\"http:\/\/demo2.tadke.com\/imgs\/cn2tech\/20220904\/ariylyj13gk2990.jpg\" \/><\/p>\n<p id=\"156H45LT\">\u516c\u53f8\u65b0\u5ba2\u6237\u89c4\u6a21\u4e0e\u8001\u5ba2\u6237\u89c4\u6a21\u95f4\u5177\u6709\u6781\u5f3a\u76f8\u5173\u6027\uff1a\u65b0\u5ba2\u6237\u5c06\u5728\u4e0e\u516c\u53f8\u7684\u6301\u7eed\u5408\u4f5c\u4e2d\u88ab\u5b75\u80b2\u6210 \u4e3a\u8001\u5ba2\u6237\uff0c\u800c\u8001\u5ba2\u6237\u5bf9\u516c\u53f8\u57f9\u517b\u57fa\u7684\u6b63\u9762\u53cd\u9988\u5c06\u4fc3\u8fdb\u516c\u53f8\u7684\u4ea7\u54c1\u54c1\u724c\u529b\u589e\u957f\uff0c\u8fdb\u800c\u63d0\u5347\u516c\u53f8\u7684\u65b0 \u5ba2\u6237\u83b7\u53d6\u80fd\u529b\u3002<\/p>\n<p>\u4e8c\u3001 \u884c\u4e1a\u524d\u666f\uff1a\u5177\u5907\u9ad8\u58c1\u5792\u9ad8\u589e\u957f\u7279\u6027\uff0c\u56fd\u4ea7\u66ff\u4ee3\u9a71\u52a8\u529b\u5341\u8db3<\/p>\n<p id=\"156H45LU\">\u57f9\u517b\u57fa\u5e7f\u6cdb\u7528\u4e8e\u751f\u7269\u5236\u54c1\u751f\u4ea7\u9886\u57df\u548c\u79d1\u5b66\u7814\u7a76\u9886\u57df\uff0c\u5728\u751f\u7269\u5236\u836f\u751f\u4ea7\u9886\u57df\u7684\u5e94\u7528\u4e3b\u8981\u5305\u62ec\u91cd \u7ec4\u86cb\u767d\/\u6297\u4f53\u836f\u7269\u751f\u4ea7\u3001\u75ab\u82d7\u751f\u4ea7\u3001\u57fa\u56e0\u6cbb\u7597\/\u7ec6\u80de\u6cbb\u7597\u836f\u7269\u751f\u4ea7\uff0c\u5728\u79d1\u5b66\u7814\u7a76\u9886\u57df\u7684\u5e94\u7528\u5219\u5305\u62ec \u836f\u7269\u7814\u7a76\u5f00\u53d1\u548c\u836f\u7269\u4f5c\u7528\u673a\u7406\u3001\u57fa\u56e0\u529f\u80fd\u3001\u75be\u75c5\u53d1\u751f\u673a\u7406\u7814\u7a76\u7b49\u57fa\u7840\u7814\u7a76\u3002<\/p>\n<p id=\"156H45LV\"><strong>(\u4e00) \u65e0\u8840\u6e05\u57f9\u517b\u57fa\u4e0d\u65ad\u63a8\u5e7f\uff0c\u540c\u65f6\u5728\u7814\u53d1\u548c\u751f\u4ea7\u73af\u8282\u63d0\u9ad8\u884c\u4e1a\u8fdb\u5165\u58c1\u5792<\/strong><\/p>\n<p id=\"156H45M0\">\u56fd\u5185\u57f9\u517b\u57fa\u5e02\u573a\u4e2d\u65e0\u8840\u6e05\u5360\u6bd4\u5c06\u8fdb\u4e00\u6b65\u63d0\u5347\u3002\u6839\u636e\u5f17\u82e5\u65af\u7279\u6c99\u5229\u6587\uff0c\u56fd\u5185\u57f9\u517b\u57fa\u5e02\u573a\u89c4\u6a21\u5728 2021 \u5e74\u8fbe 26.3 \u4ebf\u4eba\u6c11\u5e01\uff0c\u5728 2017-2021 \u5e74\u590d\u5408\u5e74\u589e\u957f\u7387\u8fbe 44.0%\uff0c\u9884\u8ba1\u81f3 2026 \u5e74\u5e02\u573a\u89c4\u6a21\u5c06\u8fbe 71.0 \u4ebf\u4eba\u6c11\u5e01\uff0c\u5728 2021-2026 \u5e74\u590d\u5408\u5e74\u589e\u957f\u7387\u4ecd\u8fbe 22.0%\u7684\u8f83\u9ad8\u6c34\u5e73\u3002\u5728\u6574\u4f53\u57f9\u517b\u57fa\u5e02\u573a\u4e2d\uff0c\u65e0 \u8840\u6e05\u57f9\u517b\u57fa\u7684\u6536\u5165\u5360\u6bd4\u81ea 2017 \u5e74\u7684 49%\u63d0\u5347\u81f3 2021 \u5e74\u7684 65%\uff0c\u9884\u8ba1\u65e0\u8840\u6e05\u57f9\u517b\u57fa\u5728\u672a\u6765\u5c06\u53d7\u66f4\u591a 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id=\"156H45MD\">2\u3001\u4ece\u83b7\u6279\u4e0a\u5e02\u7684\u60c5\u51b5\u770b\uff0c\u56fd\u4ea7\u86cb\u767d\/\u6297\u4f53\u836f\u5904\u5728\u4e0a\u5e02\u7206\u53d1\u671f\uff0c\u54c1\u79cd\u65e5\u76ca\u4e30\u5bcc\uff0c\u6108\u6765\u6108\u591a\u7684\u4f01 \u4e1a\u5c06\u56fd\u4ea7\u86cb\u767d\/\u6297\u4f53\u836f\u63a8\u5411\u5e02\u573a\u3002\u81ea 2018 \u5e74\u9996\u4e2a\u56fd\u4ea7\u539f\u521b PD-1 \u5355\u6297\u83b7\u6279\u8d77\uff0c\u91cd\u78c5\u56fd\u4ea7\u751f\u7269\u836f\u6301\u7eed \u5bc6\u96c6\u4e0a\u5e02\uff0c2018\/2019\/2020\/2021 \u5e74\/2022 \u5e74 1-7 \u6708\u56fd\u4ea7\u86cb\u767d\/\u6297\u4f53\u836f\u83b7\u6279\u6570\u91cf\u5206\u522b\u8fbe 2\/6\/7\/16\/8 \u4e2a\uff0c\u5448\u73b0\u5feb\u901f\u589e\u52a0\u8d8b\u52bf\uff0c\u5df2\u83b7\u6279\u7684\u56fd\u4ea7\u86cb\u767d\/\u6297\u4f53\u836f\u9010\u6e10\u8986\u76d6\u591a\u79cd\u70ed\u95e8\u9776\u70b9\u5355\u6297\u3001\u65b0\u5174\u9776\u70b9\u5355\u6297\u3001 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id=\"156H45MK\">\u590d\u76d8\u57f9\u517b\u57fa\u5e02\u573a\u7684\u56fd\u4ea7\u4efd\u989d\u53d8\u5316\uff0c\u53ef\u89c1\u56fd\u4ea7\u57f9\u517b\u57fa\u5728\u56fd\u5185\u5916\u7684\u75ab\u60c5\u5dee\u5f02\u4e2d\u663e\u73b0\u51fa\u4e86\u8d27\u671f\u7a33\u5b9a \u7684\u4f18\u52bf\u3002\u56fd\u5185\u57f9\u517b\u57fa\u5e02\u573a\u7684\u56fd\u4ea7\u4efd\u989d\u5728 2016-2019 \u5e74\u4ece 18.6%\u7a33\u6b65\u589e\u957f\u81f3 20.4%\uff0c\u800c\u5728\u6d77\u5916\u75ab\u60c5\u4e25 \u91cd\u6076\u5316\u7684 2020 \u5e74\u63d0\u5347\u81f3 22.8%\uff0c\u540c\u6bd4\u63d0\u5347\u901f\u5ea6\u7565\u6709\u52a0\u5feb\uff0c\u63a8\u6d4b\u662f\u7531\u4e8e\u4e00\u4e9b\u5ba2\u6237\u8003\u8651\u5230\u6d77\u5916\u57f9\u517b\u57fa \u5728\u7279\u6b8a\u65f6\u671f\u7684\u539f\u6750\u6599\u4f9b\u5e94\u3001\u89c4\u6a21\u5316\u751f\u4ea7\u3001\u7ec8\u7aef\u914d\u9001\u7b49\u73af\u8282\u7684\u4e0d\u7a33\u5b9a\u6027\u540e\u66f4\u503e\u5411\u4e8e\u9009\u62e9\u56fd\u4ea7\u57f9\u517b\u57fa\uff0c \u4fa7\u9762\u53cd\u6620\u4e86\u5ba2\u6237\u8f83\u770b\u91cd\u57f9\u517b\u57fa\u7684\u8d27\u671f\u7a33\u5b9a\u6027\u3002 \u5728\u66f4\u4e3a\u9ad8\u7aef\u7684\u86cb\u767d\/\u6297\u4f53\u57f9\u517b\u57fa\u5e02\u573a\uff0c\u4f30\u8ba1\u76ee\u524d\u56fd\u4ea7\u4efd\u989d\u660e\u663e\u4f4e\u4e8e\u6574\u4f53\u57f9\u517b\u57fa\u5e02\u573a\u7684\u56fd\u4ea7\u4efd\u989d\uff0c\u6709\u66f4\u5927\u7684\u63d0\u5347\u7a7a\u95f4\u3002\u5728 2020 \u5e74 Gibco\u3001HyClone\u3001Merck \u5728\u4e2d\u56fd\u7684\u86cb\u767d\/\u6297\u4f53\u836f\u57f9\u517b\u57fa\u6536\u5165\u5206 \u522b\u4e3a 3.1\u30011.6\u30011.2 \u4ebf\u5143\uff0c\u5360\u56fd\u5185\u86cb\u767d\/\u6297\u4f53\u57f9\u517b\u57fa\u5e02\u573a\u7684 43%\u300122%\u300117%\uff0c\u4e09\u5bb6\u6d77\u5916\u57f9\u517b\u57fa\u9f99\u5934 \u7684\u4e2d\u56fd\u533a\u57f9\u517b\u57fa\u6536\u5165\u7ed3\u6784\u76f8\u4f3c\uff0c\u86cb\u767d\/\u6297\u4f53\u57f9\u517b\u57fa\u6536\u5165\u5747\u5360\u603b\u57f9\u517b\u57fa\u6536\u5165\u7684 60%\u5de6\u53f3\uff0c\u5047\u8bbe Corning\u3001 Lonza \u7684\u4e2d\u56fd\u533a\u57f9\u517b\u57fa\u6536\u5165\u4e2d\uff0c\u4ea6\u6709 60%\u4e3a\u86cb\u767d\/\u6297\u4f53\u57f9\u517b\u57fa\u6536\u5165\uff0c\u5219\u5728 2020 \u5e74 7.3 \u4ebf\u89c4\u6a21\u7684\u56fd\u5185 \u86cb\u767d\/\u6297\u4f53\u57f9\u517b\u57fa\u5e02\u573a\u4e2d\uff0c\u56fd\u4ea7\u4efd\u989d\u7684\u6700\u5927\u503c\u4e3a 12.8%\uff0c\u76f8\u5bf9\u4e8e\u6574\u4f53\u57f9\u517b\u57fa\u5e02\u573a\u6709\u66f4\u5927\u7684\u63d0\u5347\u7a7a\u95f4\u3002 \u57f9\u517b\u57fa\u662f\u751f\u7269\u5236\u836f\u8017\u6750\u5e02\u573a\u4e2d\u5360\u6bd4\u6700\u5927\u7684\u90e8\u5206\uff0c\u5bf9\u751f\u7269\u5236\u836f\u7684\u6210\u672c\u5f71\u54cd\u663e\u8457\u3002\u4e8e 2020 \u5e74\u5168\u7403 \u751f\u7269\u5236\u836f\u8017\u6750\u5e02\u573a\u4e2d\uff0c\u57f9\u517b\u57fa\u7684\u90e8\u5206\u5360\u6bd4\u6700\u5927\uff0c\u8fbe 35%\u3002\u57f9\u517b\u57fa\u5bf9\u6bcf\u5355\u4f4d\u751f\u7269\u836f\u7efc\u5408\u6210\u672c\u7684\u5f71\u54cd\u4e3b \u8981\u5206\u4e3a\u5355\u4ef7\u3001\u4ea7\u7269\u8868\u8fbe\u91cf\u3001\u4e0b\u6e38\u7eaf\u5316\u96be\u5ea6\u4e09\u4e2a\u65b9\u9762\uff0c\u5728\u4fdd\u8bc1\u4ea7\u7269\u8868\u8fbe\u91cf\u548c\u4e0b\u6e38\u7eaf\u5316\u6210\u672c\u7a33\u5b9a\u7684\u6761 \u4ef6\u4e0b\uff0c\u9009\u7528\u5355\u4ef7\u66f4\u4f4e\u7684\u57f9\u517b\u57fa\u5219\u80fd\u591f\u663e\u8457\u964d\u4f4e\u751f\u7269\u5236\u836f\u7684\u7efc\u5408\u6210\u672c\u3002<\/p>\n<p class=\"f_center\"><img decoding=\"async\" src=\"http:\/\/demo2.tadke.com\/imgs\/cn2tech\/20220904\/mtqkpd2xjay2994.jpg\" \/><\/p>\n<p id=\"156H45MN\">\u533b\u4fdd\u76ee\u5f55\u8c03\u6574\u53ca\u96c6\u91c7\u6269\u56f4\u5c06\u4e3a\u56fd\u5185\u836f\u4f01\u957f\u671f\u5e26\u6765\u964d\u672c\u52a8\u529b\u3002\u81ea\u56fd\u5bb6\u533b\u4fdd\u5c40\u6210\u7acb\u4ee5\u6765\uff0c\u5df2\u8fde\u7eed 4 \u5e74\u5f00\u5c55\u56fd\u5bb6\u533b\u4fdd\u836f\u54c1\u76ee\u5f55\u8c03\u6574\u5de5\u4f5c \uff0c\u8c03\u51fa\u4e00\u6279\u201c\u795e\u836f\u201d\u53ca\u201c\u50f5\u5c38\u836f\u201d\u7684\u540c\u65f6\uff0c\u6301\u7eed\u8c03\u5165\u91cd\u78c5\u751f \u7269\u836f\uff0c4 \u6b3e PD-1 \u5355\u6297\u3001\u6cf0\u5b83\u897f\u666e\u3001\u7ef4\u8fea\u897f\u59a5\u5355\u6297\u5728\u8c03\u5165\u76ee\u5f55\u540e\u4ef7\u683c\u964d\u5e45\u9ad8\u8fbe 62-85%\u5de6\u53f3\uff0c\u7531\u6b64\u56fd \u5185\u836f\u4f01\u5c06\u4ea7\u751f\u5f3a\u70c8\u7684\u964d\u672c\u9700\u6c42\uff0c\u4ece\u800c\u5bf9\u9ad8\u6027\u4ef7\u6bd4\u56fd\u4ea7\u57f9\u517b\u57fa\u7684\u91c7\u8d2d\u9700\u6c42\u5927\u5e45\u589e\u52a0\u3002\u8fd1\u4e24\u5e74\u6765\u653f\u7b56 \u4fe1\u53f7\u9891\u51fa\uff0c\u663e\u793a\u51fa\u56fd\u5bb6\u96c6\u91c7\u8303\u56f4\u5c06\u5728\u672a\u6765\u5411\u751f\u7269\u5236\u54c1\u62d3\u5c55\uff0c\u7531\u6b64\u53ef\u63a8\u6d4b\uff0c\u56fd\u4ea7\u751f\u7269\u836f\u9664\u8c03\u5165\u56fd\u5bb6 \u533b\u4fdd\u76ee\u5f55\u4ee5\u5916\uff0c\u5c06\u8fce\u6765\u201c\u4ee5\u91cf\u6362\u4ef7\u201d\u7684\u7b2c\u4e8c\u66f2\u7ebf\uff0c\u4e3a\u56fd\u4ea7\u57f9\u517b\u57fa\u6253\u5f00\u589e\u957f\u65b0\u7a7a\u95f4\u3002<\/p>\n<p>\u4e09\u3001 \u62a4\u57ce\u6cb3\uff1a\u57f9\u517b\u57fa\u4e0e CDMO \u53cc\u5bfc\u6d41\uff0c\u4ea7\u54c1\u529b\u4e0e\u5ba2\u6237\u7f51\u4e92\u4fc3\u8fdb<\/p>\n<p id=\"156H45MO\"><strong>(\u4e00) CDMO \u670d\u52a1\u4e0d\u65ad\u5b8c\u5584\uff0c\u4e3a\u57f9\u517b\u57fa\u5bfc\u6d41\u65b0\u5ba2\u6237+\u7a33\u56fa\u539f\u6709\u5ba2\u6237<\/strong><\/p>\n<p id=\"156H45MP\">\u516c\u53f8\u4ece\u521b\u7acb\u8d77\u4e0d\u65ad\u5b8c\u5584\u86cb\u767d\/\u6297\u4f53\u836f\u7269\u5f00\u53d1\u670d\u52a1\u5e73\u53f0\uff0c\u65e9\u671f\u4ece\u7ec6\u80de\u682a\u6784\u5efa\u548c\u7ec6\u80de\u57f9\u517b\u5de5\u827a\u4f18\u5316 \u5f00\u59cb\uff0c\u4e0d\u65ad\u5ef6\u4f38\u548c\u6df1\u5316\uff0c\u73b0\u516c\u53f8\u7684 CDMO \u670d\u52a1\u6db5\u76d6\u7ec6\u80de\u682a\u6784\u5efa\u3001\u5de5\u827a\u5f00\u53d1\uff08\u5305\u62ec\u4e0a\u6e38\u7ec6\u80de\u57f9\u517b\u5de5\u827a \u5f00\u53d1\u3001\u4e0b\u6e38\u7eaf\u5316\u5de5\u827a\u5f00\u53d1\u3001\u5236\u5242\u5904\u65b9\u5de5\u827a\u5f00\u53d1\uff09\u3001\u4e2d\u8bd5\u751f\u4ea7\u4e09\u4e2a\u9636\u6bb5\uff0c\u662f\u7ec6\u80de\u57f9\u517b\u57fa\u8fdb\u5165\u5230\u836f\u7269\u7814 \u7a76\u548c\u5546\u4e1a\u5316\u751f\u4ea7\u7684\u6700\u4f73\u5207\u5165\u65f6\u673a\uff0c\u516c\u53f8\u5df2\u6210\u529f\u5c06\u4e24\u5927\u4e1a\u52a1\u6709\u673a\u7ed3\u5408\uff0c\u5b9e\u73b0\u4e86\u5ba2\u6237\u7684\u53cc\u5411\u8f6c\u5316\uff0c\u9884 \u8ba1\u672a\u6765\u516c\u53f8\u80fd\u591f\u51ed\u501f\u6b64\u4e1a\u52a1\u6a21\u5f0f\u7684\u4f18\u52bf\u6301\u7eed\u4e3a\u57f9\u517b\u57fa\u4e1a\u52a1\u5bfc\u6d41\u65b0\u5ba2\u6237\uff0c\u5e76\u7a33\u56fa\u539f\u6709\u5ba2\u6237\u3002<\/p>\n<p id=\"156H45MQ\">\u516c\u53f8\u5728\u7ec6\u80de\u682a\u6784\u5efa\u548c\u7ec6\u80de\u57f9\u517b\u5de5\u827a\u9886\u57df\u5177\u5907\u4f18\u79c0\u7684 CDMO \u670d\u52a1\u80fd\u529b\uff0c\u5df2\u7ecf\u6210\u529f\u4e3a\u6570\u5341\u4e2a\u521b\u65b0\u836f \u5f00\u53d1\u7ec6\u80de\u682a\uff0c\u534f\u52a9\u836f\u54c1\u8fdb\u5165\u5230\u4e34\u5e8a\u9636\u6bb5\uff0c\u80fd\u591f\u4ece\u6e90\u5934\u9501\u5b9a\u672a\u6765\u5ba2\u6237\u836f\u54c1\u4e0a\u5e02\u540e\u7684\u57f9\u517b\u57fa\u5e02\u573a\uff0c\u9ad8 \u6548\u53d1\u6325 CDMO \u4e0e\u57f9\u517b\u57fa\u9500\u552e\u95f4\u7684\u534f\u540c\u4f5c\u7528\u3002<\/p>\n<p id=\"156H45MR\"><strong>(\u4e8c) \u5728\u9ad8\u7aef\u57f9\u517b\u57fa\u9886\u57df\u5c45\u672c\u571f\u54c1\u724c\u4e4b\u9996\uff0cCHO \u4ea7\u54c1\u7e41\u591a\u4e14\u9002\u7528\u8303\u56f4\u5e7f\u6cdb<\/strong><\/p>\n<p id=\"156H45MS\">\u516c\u53f8\u5728\u86cb\u767d\/\u6297\u4f53\u57f9\u517b\u57fa\u5e02\u573a\u4e2d\u7684\u4efd\u989d\u5c45\u672c\u571f\u54c1\u724c\u4e4b\u9996\u3002\u6839\u636e\u5f17\u82e5\u65af\u7279\u6c99\u5229\u6587\uff0c\u76ee\u524d\u516c\u53f8\u4e8e\u56fd \u5185\u86cb\u767d\/\u6297\u4f53\u836f\u57f9\u517b\u57fa\u5e02\u573a\u4e2d\u7684\u5360\u6709\u7387\u8fbe 6%\uff0c\u5c45\u672c\u571f\u4f01\u4e1a\u4e4b\u9996\uff0c\u4ec5\u6b21\u4e8e\u4e09\u5927\u8fdb\u53e3\u54c1\u724c\uff0c\u8bf4\u660e\u516c\u53f8\u5728 \u9ad8\u7aef\u57f9\u517b\u57fa\u9886\u57df\u5177\u5907\u7edd\u4f73\u7684\u884c\u4e1a\u5730\u4f4d\uff0c\u5177\u5907\u4e0e\u8fdb\u53e3\u54c1\u724c\u540c\u53f0\u7ade\u4e89\u7684\u80fd\u529b\u3002 CHO \u7ec6\u80de\u662f\u91cd\u7ec4\u86cb\u767d\/\u6297\u4f53\u8868\u8fbe\u6700\u91cd\u8981\u5e73\u53f0\u3002\u6839\u636e\u300aBiopharmaceutical benchmarks 2018\u300b\uff0c \u5728 2014 \u5e74\u81f3 2018 \u5e74 7 \u6708\u7f8e\u56fd\u548c\u6b27\u76df\u6279\u51c6\u4e0a\u5e02\u7684\u6240\u6709\u5355\u6297\u836f\u4e2d\uff0c84%\u6765\u6e90\u4e8e CHO \u7ec6\u80de\u3002<\/p>\n<p id=\"156H45MT\">\u4ea7\u54c1\u533a\u5206\u5ea6\u548c\u9002\u7528\u8303\u56f4\u65b9\u9762\uff0c\u516c\u53f8\u7684 CHO \u76ee\u5f55\u57f9\u517b\u57fa\u4ee5\u5b8c\u5168\u5316\u5b66\u6210\u5206\u786e\u5b9a\u7684\u57f9\u517b\u57fa\u4e3a\u4e3b\uff0c\u81ea \u516c\u53f8\u521b\u7acb\u4ee5\u6765\u79ef\u6781\u9488\u5bf9 CHO \u7ec6\u80de\u8fdb\u884c\u57fa\u7840\u57f9\u517b\u57fa\u4ea7\u54c1\u8fed\u4ee3\uff0c\u5e76\u63a8\u51fa\u4e0e\u4e4b\u642d\u914d\u7684\u8865\u6599\u57f9\u517b\u57fa\u3001\u8d85\u6d53 \u7f29\u8865\u6599\u4e0e\u6dfb\u52a0\u5242\u7b49\u4ea7\u54c1\uff0c\u76ee\u524d\u9002\u7528\u7ec6\u80de\u8303\u56f4\u5df2\u8986\u76d6 CHO-K1\u3001CHO-DG44\u3001CHO-S \u548c CHOZN \u7b49\u4e0d\u540c\u4e9a \u578b\uff0c\u53ef\u63d0\u4f9b\u5e72\u7c89\u548c\u6db2\u4f53\u4e24\u79cd\u5242\u578b\uff0c\u53ef\u652f\u6301\u7ec6\u80de\u7684\u57fa\u672c\u751f\u957f\u589e\u6b96\uff08\u5305\u62ec\u590d\u82cf\u3001\u4f20\u4ee3\u53ca\u9ad8\u5bc6\u5ea6\u6d41\u52a0\u57f9 \u517b\uff09\u6216\u77ac\u65f6\/\u7a33\u5b9a\u8f6c\u67d3\uff0c\u4e14\u5728\u7ec4\u5206\u9650\u5b9a\u3001PH \u503c\u3001\u6709\u6548\u671f\u7b49\u4ea7\u54c1\u53c2\u6570\u4e0a\u8fdb\u4e00\u6b65\u505a\u51fa\u4e86\u533a\u5206\uff0c\u6839\u636e\u516c\u53f8 \u5b98\u7f51\u548c\u56fd\u5185\u5176\u4ed6\u4e3b\u8981\u57f9\u517b\u57fa\u5382\u5546\u5b98\u7f51\u62ab\u9732\uff0c\u516c\u53f8\u7684 CHO \u76ee\u5f55\u57f9\u517b\u57fa\u4ea7\u54c1\u77e9\u9635\u5728\u533a\u5206\u5ea6\u548c\u9002\u7528\u8303\u56f4 \u65b9\u9762\u5177\u5907\u4e00\u5b9a\u4f18\u52bf\uff0c\u53ef\u5728\u8f83\u5927\u7a0b\u5ea6\u4e0a\u6ee1\u8db3\u4e0d\u540c\u5ba2\u6237\u7684\u9700\u6c42\u3002<\/p>\n<p id=\"156H45MU\">\u4ea7\u54c1\u54c1\u8d28\u65b9\u9762\uff0c\u6839\u636e\u516c\u53f8\u62ab\u9732\u7684\u5ba2\u6237\u5728\u9879\u76ee\u4e2d\u4f7f\u7528\u5965\u6d66\u8fc8 CHO \u76ee\u5f55\u57f9\u517b\u57fa\u548c\u8fdb\u53e3\u57f9\u517b\u57fa\u7684\u5bf9 \u6bd4\u6570\u636e\uff0c\u516c\u53f8\u4e24\u4ee3 CHO \u57f9\u517b\u57fa\u7684\u54c1\u8d28\u5747\u53ef\u5ab2\u7f8e\u56fd\u9645\u6c34\u51c6\u3002 OPM-CHO CD07\uff082016 \u5e74 SDS \u751f\u6548\uff0c\u4e0d\u542b\u751f\u957f\u56e0\u5b50\uff09\uff1a\u7ec6\u80de\u751f\u957f\u65b9\u9762\uff0c\u5728\u57f9\u517b 14 \u5929\u5185\uff0c Process 1 \u7ec4\uff08\u516c\u53f8\u57f9\u517b\u57fa+\u5b9a\u5236\u5316\u5de5\u827a 1\uff09\u548c Process 2 \u7ec4\uff08\u516c\u53f8\u57f9\u517b\u57fa+\u5b9a\u5236\u5316\u5de5\u827a 2\uff09\u7684\u6d3b\u7ec6\u80de \u5bc6\u5ea6\u5cf0\u503c\u7565\u9ad8\u4e8e Control \u7ec4\uff08\u8fdb\u53e3\u57f9\u517b\u57fa\uff09\uff0c\u5728\u57f9\u517b\u81f3 14 \u5929\u540e\uff0cControl \u7ec4\u7684\u6d3b\u7ec6\u80de\u5bc6\u5ea6\u548c\u7ec6\u80de\u6d3b \u7387\u5747\u663e\u8457\u4e0b\u964d\uff0c\u800c Process 1 \u7ec4\u548c Process 2 \u7ec4\u7684\u6d3b\u7ec6\u80de\u5bc6\u5ea6\u4e0b\u964d\u5e45\u5ea6\u76f8\u5bf9\u8f7b\u5fae\uff0c\u7ec6\u80de\u6d3b\u7387\u57fa\u672c\u7a33 \u5b9a\uff0cProcess 2 \u7ec4\u5728\u7b2c 16 \u5929\u6d3b\u7ec6\u80de\u5bc6\u5ea6\u4ecd\u80fd\u7ef4\u6301\u5728 30\u00d7106cells\/ml\uff0c\u7ec6\u80de\u6d3b\u7387\u7ef4\u6301\u5728 98%\uff1b\u6297\u4f53\u8868 \u8fbe\u65b9\u9762\uff0cControl \u7ec4\/Process1 \u7ec4\/Process2 \u7ec4\u7684\u6297\u4f53\u8868\u8fbe\u91cf\u5206\u522b\u4e3a 4.83\/6.39\/8.4 g\/L\uff0c\u4f7f\u7528\u516c\u53f8\u57f9\u517b\u57fa \u7684\u4e24\u4e2a\u5de5\u827a\u7ec4\u7684\u6297\u4f53\u8868\u8fbe\u91cf\u5747\u663e\u8457\u9ad8\u4e8e\u4f7f\u7528\u8fdb\u53e3\u57f9\u517b\u57fa\u4e00\u7ec4\u3002<\/p>\n<p class=\"f_center\"><img decoding=\"async\" src=\"http:\/\/demo2.tadke.com\/imgs\/cn2tech\/20220904\/inltdcescef2995.jpg\" \/><\/p>\n<p id=\"156H45N1\">\u6536\u5165\u89c4\u6a21\u65b9\u9762\uff0c\u516c\u53f8\u7684 CHO \u57f9\u517b\u57fa\u9500\u552e\u89c4\u6a21\u5728 2019\/2020\/2021 \u5e74\u5206\u522b\u8fbe 1600\/2942\/8164 \u4e07 \u5143\uff0c\u59cb\u7ec8\u8fdc\u8d85\u56fd\u5185\u4e3b\u8981\u7ade\u4e89\u5bf9\u624b\uff0c\u4e14\u5728 2019-2021 \u5e74\u5b9e\u73b0\u4e86\u52a0\u901f\u589e\u957f\uff0c\u9884\u8ba1\u6709\u671b\u5728\u56fd\u4ea7 CHO \u57f9\u517b \u57fa\u4e2d\u957f\u671f\u4fdd\u6301\u5e02\u573a\u4e3b\u5bfc\u8005\u7684\u5730\u4f4d\uff0c\u5728\u4e0b\u6e38\u884c\u4e1a\u4e2d\u4fdd\u6301\u826f\u597d\u53e3\u7891\u3002<\/p>\n<p id=\"156H45N2\">CHO \u57f9\u517b\u57fa\u677f\u5757\u5728\u540e\u75ab\u60c5\u671f\u5177\u5907\u6210\u957f\u786e\u5b9a\u6027\u3002\u76ee\u524d\u5728\u56fd\u5185\u5916 CHO \u7ec6\u80de\u5747\u4e3b\u8981\u7528\u4e8e\u86cb\u767d\/\u6297\u4f53 \u836f\u7684\u7814\u53d1\u548c\u751f\u4ea7\uff0c\u800c\u86cb\u767d\/\u6297\u4f53\u836f\u7684\u9002\u5e94\u75c7\u96c6\u4e2d\u5728\u80bf\u7624\u548c\u514d\u75ab\u708e\u75c7\u7b49\u9886\u57df\uff0c\u4e0e\u65b0\u51a0\u9632\u6cbb\u5219\u4e3b\u8981\u901a\u8fc7 \u91cd\u7ec4\u86cb\u767d\u75ab\u82d7\u548c\u4e2d\u548c\u6297\u4f53\u76f8\u5173\u8054\uff0c\u5176\u5e74\u4ea7\u91cf\u4e4b\u548c\u5728\u6240\u6709\u86cb\u767d\/\u6297\u4f53\u836f\u4e2d\u5360\u6bd4\u6781\u5c0f\uff0c\u56e0\u6b64\u516c\u53f8\u7684 CHO \u57f9\u517b\u57fa\u677f\u5757\u6536\u5165\u4e3b\u8981\u6765\u81ea\u975e\u75ab\u60c5\u76f8\u5173\u7684\u9879\u76ee\uff0c\u5728\u540e\u75ab\u60c5\u671f\u4ecd\u6709\u6210\u957f\u786e\u5b9a\u6027\u3002<\/p>\n<p id=\"156H45N3\"><strong>(\u4e09) \u5ba2\u6237\u50a8\u5907\u4e30\u5bcc\u4e14\u5728\u65b0\u5174\u9886\u57df\u5177\u5907\u8ba4\u53ef\u5ea6\uff0c\u4e0d\u65ad\u4e0e\u91cd\u78c5\u5ba2\u6237\u6df1\u5316\u5408\u4f5c<\/strong><\/p>\n<p id=\"156H45N4\">\u516c\u53f8\u5ba2\u6237\u7c7b\u578b\u4e30\u5bcc\uff0c\u5728\u751f\u7269\u836f\u521b\u65b0\u9886\u57df\u5177\u5907\u6743\u5a01\u80cc\u4e66\u3002\u516c\u53f8\u7684\u5ba2\u6237\u7f51\u7edc\u5df2\u8986\u76d6\u56fd\u836f\u96c6\u56e2\u7b49\u5927 \u578b\u56fd\u6709\u4f01\u4e1a\u3001\u6052\u745e\u533b\u836f\u7b49 Bigpharma\u3001\u541b\u5b9e\u751f\u7269\u3001\u767e\u6d4e\u795e\u5dde\u7b49 Biopharma\u3001\u77e5\u540d Biotech\u3001\u836f\u660e\u5eb7 \u5fb7\u7b49\u5927\u578b CXO\u3001\u79d1\u7814\u9662\u6821\u7b49\uff0c\u4e14\u5df2\u5411\u591a\u4e2a\u6d77\u5916\u5ba2\u6237\u63d0\u4f9b\u4ea7\u54c1\u53ca\u670d\u52a1\uff0c\u5ba2\u6237\u7c7b\u578b\u4e30\u5bcc\u3002\u516c\u53f8\u5728\u4e09\u5e74\u524d \u5373\u4e0e\u5eb7\u65b9\u751f\u7269\u3001\u541b\u5b9e\u751f\u7269\u3001\u767e\u6d4e\u795e\u5dde\u7b49\u521b\u65b0\u5b9e\u529b\u6781\u5f3a\u3001\u5177\u5907\u884c\u4e1a\u5f71\u54cd\u529b\u7684\u5ba2\u6237\u8fbe\u6210\u5408\u4f5c\uff0c\u8fd1\u4e09\u5e74 \u6301\u7eed\u52a9\u529b\u53cc\u6297\u3001\u957f\u6548\u516b\u56e0\u5b50\u3001DNA \u75ab\u82d7\u3001ADC \u7b49\u591a\u4e2a\u65b0\u5174\u7c7b\u578b\u751f\u7269\u836f\u9879\u76ee\u53d6\u5f97\u4e34\u5e8a\u7814\u7a76\u6216\u5b66\u672f\u7814\u7a76 \u7684\u8fdb\u5c55\uff0c\u663e\u793a\u5728\u521b\u65b0\u54c1\u79cd\u7684\u7814\u53d1\u751f\u4ea7\u65b9\u9762\uff0c\u516c\u53f8\u5df2\u5177\u5907\u4e00\u5b9a\u7684\u884c\u4e1a\u8ba4\u53ef\u5ea6\uff0c\u57f9\u517b\u57fa\u4ea7\u54c1\u529b\u548c CDMO \u670d\u52a1\u529b\u53ef\u6ee1\u8db3\u65b0\u7c7b\u578b\u751f\u7269\u836f\u7684\u8981\u6c42\uff0c\u6709\u671b\u5728\u56fd\u5185\u751f\u7269\u836f\u884c\u4e1a\u7684\u521b\u65b0\u52a0\u901f\u4e0b\u8fce\u6765\u66f4\u591a\u6210\u957f\u673a\u9047\u3002<\/p>\n<p id=\"156H45N5\">\u91cd\u78c5\u5ba2\u6237\u5b75\u80b2\u6210\u6548\u826f\u597d\uff0c\u6709\u671b\u4fc3\u8fdb\u57f9\u517b\u57fa\u4ea7\u54c1\u5feb\u901f\u8fed\u4ee3\u3002\u516c\u53f8\u4e0e\u56fd\u836f\u96c6\u56e2\u3001\u957f\u6625\u91d1\u8d5b\u3001\u5eb7\u65b9 \u751f\u7269\u7b49\u91cd\u78c5\u5ba2\u6237\u4fdd\u6301\u7740\u957f\u671f\u5408\u4f5c\uff0c\u968f\u7740\u5176\u9879\u76ee\u7814\u7a76\u9636\u6bb5\u5411\u540e\u63a8\u8fdb,\u6765\u81ea\u4ee5\u4e0a\u4e09\u4f4d\u5ba2\u6237\u7684\u57f9\u517b\u57fa\u6536\u5165 \u5728 2019-2021 \u5e74\u5927\u5e45\u589e\u52a0\uff0c\u516c\u53f8\u4e0e\u5927\u5ba2\u6237\u95f4\u7684\u5408\u4f5c\u7c98\u6027\u6301\u7eed\u63d0\u5347\uff0c\u4e00\u65b9\u9762\u4e3a\u672a\u6765\u5927\u989d\u8ba2\u5355\u7684\u589e\u52a0 \u63d0\u4f9b\u4fdd\u969c\uff0c\u53e6\u4e00\u65b9\u9762\u53ef\u5728\u4e0e\u5ba2\u6237\u7684\u4ea4\u6d41\u5408\u4f5c\u4e2d\u5b9e\u65f6\u66f4\u65b0\u4e0b\u6e38\u884c\u4e1a\u7684\u9700\u6c42\uff0c\u4ee5\u5feb\u901f\u6355\u6349\u4ea7\u54c1\u8fed\u4ee3\u65b9 \u5411\u3002<\/p>\n<p class=\"f_center\"><img decoding=\"async\" src=\"http:\/\/demo2.tadke.com\/imgs\/cn2tech\/20220904\/uydpfjtagwe2996.jpg\" \/><\/p>\n<p id=\"156H45N8\">\u516c\u53f8\u57f9\u517b\u57fa\u9879\u76ee\u4e2d\u5df2\u62ab\u9732\u7684\u76ee\u6807\u4ea7\u54c1\u5e02\u573a\u524d\u666f\u53ef\u671f\uff0c\u6709\u671b\u5728\u5546\u4e1a\u5316\u9636\u6bb5\u4e3a\u516c\u53f8\u57f9\u517b\u57fa\u7684\u9500\u552e \u5e26\u6765\u957f\u671f\u9a71\u52a8\u30021\uff09\u4e34\u5e8a\u7814\u7a76\u9636\u6bb5\u90e8\u5206\uff1aJS004 \u662f\u5168\u7403\u9996\u4e2a\u83b7\u6279 IND \u7684\u6297 BTLA \u5355\u6297\uff0cLBL-007 \u662f \u56fd\u5185\u7814\u53d1\u8fdb\u5ea6\u8f83\u5feb\u7684\u6297 LAG-3 \u5355\u6297\uff0c\u4e24\u6b3e\u4ea7\u54c1\u5747\u662f\u65b0\u4e00\u4ee3\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\uff0c\u5177\u6709\u4e0e\u6297 PD-(L)1 \u5355\u6297\u548c\u591a\u79cd\u9776\u5411\u836f\u8054\u5408\u6cbb\u7597\u591a\u79cd\u80bf\u7624\u7684\u6f5c\u529b\uff1bEX103 \u548c EMB-06 \u662f\u4e24\u6b3e\u53cc\u6297\uff0c\u800c\u53cc\u6297\u5728\u5168\u7403\u53ca\u56fd \u5185\u5747\u5904\u5728\u5e02\u573a\u89c4\u6a21\u5feb\u901f\u6269\u5f20\u7684\u9636\u6bb5\uff1b\u56fd\u4ea7\u957f\u6548\u516b\u56e0\u5b50\u517c\u5177\u7528\u836f\u4fbf\u5229\u6027\u548c\u4ef7\u683c\u4f18\u52bf\uff0c\u6709\u671b\u5728\u83b7\u6279\u540e \u5feb\u901f\u653e\u91cf\uff1b2\uff09\u5df2\u5546\u4e1a\u5316\u90e8\u5206\uff1a\u6734\u6b23\u6c40\u662f\u7b2c\u4e03\u6b3e\u4e0a\u5e02\u7684\u56fd\u4ea7\u8d1d\u4f10\u73e0\u5355\u6297\uff0c\u8d1d\u4f10\u73e0\u5355\u6297\u5df2\u8fdb\u5165\u533b\u4fdd\u8303 \u56f4\uff0c\u9884\u8ba1\u5ba2\u6237\u5c06\u5728\u4e3a\u6734\u6b23\u6c40\u8fdb\u5165\u533b\u4fdd\u7684\u51c6\u5907\u5de5\u4f5c\u4e2d\u8ba1\u5212\u6269\u4ea7\uff0c\u4ece\u800c\u52a0\u5927\u5bf9\u57f9\u517b\u57fa\u7684\u91c7\u8d2d\u91cf\u3002<\/p>\n<p>\u56db\u3001 \u52df\u8d44\u7528\u9014\uff1a\u63d0\u9ad8\u5927\u578b CDMO 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